Automated versus Manual Measurement of the QT Interval and Corrected QT Interval

[Corrected QT interval and corrected QT interval dispersion is worthwhile when interpreted with other repolarization measurements].

We read the article entitled ‘‘The effect of esmolol on corrected-QT interval, corrected-QT interval dispersion changes seen during anesthesia induction in hypertensive patients taking an angiotensin-converting enzyme inhibitor’’ by Ceker et al. with interest.1 The authors investigated the effects of esmolol on the hemodynamic, correctedQT (QTc) interval and corrected-QT interval dispersion (QT...

Measurement of the QT interval.

Ventricular repolarization is reflected by the T-wave of the surface electrocardiogram, the QT interval being the time taken for ventricular recovery. QT measurement has assumed clinical importance as prolongation is associated with a variety of conditions includingthe Romano-Ward' and JervellLange-Neilson syndromes, drug toxirity' and an adverse prognosis following acute myocardial infarction....

QT interval measurement: evaluation of automatic QTc measurement and new simple method to calculate and interpret corrected QT interval.

BACKGROUND Assessment of repolarization duration is often recommended to avoid administration of QT-prolonging drugs in patients with prolonged QTc interval, a frequent situation in the postoperative period. Bazett QT correction inappropriately increases QTc when heart rate is increased, and the use of the Fridericia formula may avoid a falsely prolonged QTc interval. The authors assessed autom...

Issues in QT interval measurement

The QT interval, apart from clinical implications is crucial for safety assessment of new drugs under development. A QTc prolongation of even 10 msec in a study group is a warning signal for a new drug. There are various issues involved in the measurement of the QT interval especially regarding the ending of the T wave and different morphological pattern of T-U complex. The other issue is signi...

QT Interval and QT Variability